CAY10554 是一种有效的细胞周期蛋白依赖性激酶 5 (Cdk5) 抑制剂，对 Cdk5 和 Cdk2 的 IC50 分别为 64 和 98 nM。
| Cas No. | 267654-00-2 |
| Canonical SMILES | O=C(Cc1ccccc1)Nc1ncc(s1)C(C)C |
| 分子式 | C14H16N2OS |
| 分子量 | 260.4 |
| 溶解度 | DMF: 30 mg/ml,DMSO: 30 mg/ml,DMSO:PBS (pH 7.2)(1:2): 0.3 mg/ml,Ethanol: 0.25 mg/ml |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Cyclin-dependent kinases (CDKs) are key regulators of cell cycle progression and are therefore promising therapeutic targets for cancer and neurodegenerative diseases. Cyclin-dependent kinases (CDKs) are key regulators of cell cycle progression and are therefore promising therapeutic targets for cancer and neurodegenerative diseases. CAY10554 is a potent inhibitor of Cdk5 and Cdk2, with IC50 values of 64 and 98 nM, respectively. |
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