| 包装 | 价格(元) |
| 1mg | 电议 |
| 5mg | 电议 |
| 10mg | 电议 |
| Canonical SMILES | FC(F)(F)C1=CC=C(C(NC2CCN(C(C)(C)C)CC2)=O)C(Cl)=C1 |
| 分子式 | C17H22ClF3N2O |
| 分子量 | 362.8 |
| 溶解度 | DMF: 11mg/mL,DMF:PBS (pH 7.2) (1:2): 0.3mg/mL,DMSO: 10mg/mL |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | CAY10766 is an antiviral compound.1It inhibits entry of influenza virus-like particles pseudotyped with hemagglutinin A (HA) from H5N1 influenza A virus into A549 cells (EC50= 0.24 µM). CAY10766 (1 µM) reduces H1N1 and H5N1 influenza A viral titers in infected MDCK cells. It also exhibits synergy with oseltamivir carboxylate in MDCK cells infected with the influenza A reporter PR8-NS1-Gluc virus. 1.Gaisina, I.N., Peet, N.P., Cheng, H., et al.Optimization of 4?aminopiperidines as inhibitors of influenza A viral entry that are synergistic with oseltamivirJ. Med. Chem.63(6)312-3130(2020) |
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