CAS NO: | 1216653-50-7 |
包装 | 价格(元) |
500 μg | 电议 |
1mg | 电议 |
Cas No. | 1216653-50-7 |
别名 | R18134-d5 |
Canonical SMILES | ClC1=CC=C(C([2H])([2H])OC([2H])(C2=CC=C(Cl)C=C2Cl)C([2H])(N3C=CN=C3)[2H])C(Cl)=C1 |
分子式 | C18H9Cl4D5N2O |
分子量 | 421.2 |
溶解度 | Acetonitrile: soluble,DMSO: Soluble,Methanol: Soluble |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Miconazole-d5is intended for use as an internal standard for the quantification of miconazole by GC- or LC-MS. Miconazole is an imidazole antifungal.1It is active againstC. parapsilosis,C. pseudotropicalis,C. albicans,C. neoformans,C. tropicalis, andC. guilliermondii(MICs =<0.1-10 µg/ml). It is also active against variousTrichophytonspecies,A. fumigatus,A. niger,B. brasiliensis, andB. dermatitidis. Miconazole (160 mg/kg) prevents infection withT. mentagrophytesandM. canisin mice. It also reduces lesion size in a guinea pig model ofC. albicans infection. Formulations containing miconazole have been used in the treatment of various fungal infections. 1.Sawyer, P.R., Brogden, R.N., Pinder, R.M., et al.Miconazole: A review of its antifungal activity and therapeutic efficacyDrugs9(6)406-423(1975) |