| CAS NO: | 7020-34-0 |
| 包装 | 价格(元) |
| 1mg | 电议 |
| 5mg | 电议 |
| 10mg | 电议 |
| 25mg | 电议 |
| Cas No. | 7020-34-0 |
| Canonical SMILES | C[C@]1([C@]2([C@]([C@@]3([C@@](C(C)(C(CC3)=O)C)([H])CC2)C)([H])CC4)C)[C@@]4([H])[C@]([C@@H](CC5)C(C)=C)([H])[C@@]5(CO)CC1 |
| 分子式 | C30H48O2 |
| 分子量 | 440.7 |
| 溶解度 | DMF: 30 mg/ml,DMSO: 10 mg/ml,Ethanol: 10 mg/ml |
| 储存条件 | -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | 3-Oxobetulin is a pentacyclic triterpenoid and derivative of betulinic acid that has been found inI. macropodaand has diverse biological activities.1,2,3It is active against the plant pathogenic fungiL. betulinaandL. sulphureuswhen used at a concentration of 30 µg/ml.23-Oxobetulin reduces HIV-1 replication in MT-2 cells (IC50= 4.1 µM) with a 50% cytotoxic concentration (CC50) value of greater than 100 µM.4It inhibits cadmium-induced cytotoxicity in HepG2 cells in a concentration-dependent manner.3 1.Kim, D.K., Nam, I.Y., Kim, J.W., et al.Pentacyclic triterpenoids from Ilex macropodaArch. Pharm. Res.25(5)617-620(2002) 2.Chien, S.-C., Xiao, J.-H., Tseng, Y.-H., et al.Composition and antifungal activity of balsam from Liquidambar formosana HanceHolzforschung67(3)345-351(2013) 3.Hiroya, K., Takahashi, T., Miura, N., et al.Synthesis of betulin derivatives and their protective effects against the cytotoxicity of cadmiumBioorg. Med. Chem.10(10)3229-3236(2002) 4.Callies, O., Bedoya, L.M., BeltrÁn, M., et al.Isolation, structural modification, and HIV inhibition of pentacyclic lupane-type triterpenoids from Cassine xylocarpa and Maytenus cuzcoinaJ. Nat. Prod.78(5)1045-1055(2015) |
m.cnreagent.com