| CAS NO: | 1677667-24-1 |
| 包装 | 价格(元) |
| 250mg | 电议 |
| 500mg | 电议 |
| Cas No. | 1677667-24-1 |
| Canonical SMILES | OC1=CC(C2=C3N(C(C(C4=C(C(F)(F)F)C=CC=C4Cl)=O)=N2)C=CC=C3)=CC=C1C(O)=O |
| 分子式 | C22H12ClF3N2O4 |
| 分子量 | 460.79 |
| 溶解度 | Soluble in DMSO |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | GNE-0946 is a potent and selective RORγ( RORc) agonist with an EC50 value of 4 nM for HEK-293 cell. [1]. Fauber BP, et al. Discovery of imidazo[1,5-a]pyridines and -pyrimidines as potent and selective RORc inverse agonists. Bioorg Med Chem Lett. 2015 Aug 1;25(15):2907-12. |
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