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Negletein
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Negletein图片
CAS NO:29550-13-8
包装与价格:
包装价格(元)
5mg电议
10mg电议

产品介绍
Negletein 是一种神经保护剂,可增强神经生长因子的作用并诱导 PC12 细胞中的神经突向外生长。Negletein 通过抑制 TNF-α 和 IL-1β 表现出有希望的抗炎活性,其 IC50 值分别为 16.4 和 10.8 μM。
Cas No.29550-13-8
别名黄芩素-7-甲醚; 5,6-Dihydroxy-7-methoxyflavone
Canonical SMILESO=C1C=C(C2=CC=CC=C2)OC3=CC(OC)=C(O)C(O)=C13
分子式C16H12O5
分子量284.26
溶解度Soluble in DMSO
储存条件Store at -20°C, protect from light
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Negletein is a neuroprotectant enhances the action of nerve growth factor and induces neurite outgrowth in PC12 cells. Negletein shows promising anti-inflammatory activity via inhibition of TNF-α and IL-1β with IC50 values of 16.4 and 10.8 μM, respectively[1].

[1]. Phan CW, et al. Negletein as a neuroprotectant enhances the action of nerve growth factor and induces neurite outgrowth in PC12 cells. Biofactors. 2016 Nov 12;42(6):591-599. [2]. Singh B, et al. Anti-inflammatory and immunomodulatory flavones from Actinocarya tibetica Benth.Nat Prod Res. 2013;27(23):2227-30.