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S 07662
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
S 07662图片
CAS NO:883226-64-0
包装与价格:
包装价格(元)
10mg电议
50mg电议

产品介绍
Constitutive androstane receptor (CAR) inverse agonist
Cas No.883226-64-0
Canonical SMILESCC2=C(CNC(NCC3=CC=CS3)=O)C1=CC=CC=C1O2
分子式C16H16N2O2S
分子量300.38
溶解度Soluble in DMSO
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Inverse agonist of the constitutive androstane receptor (CAR). Inhibits CAR activity via recruitment of nuclear receptor co-repressor (NCoR). Suppresses CITCO-induced CYP2B6 gene expression in human primary hepatocytes.

Küblbeck et al (2011) New in vitro tools to study human constitutive androstane receptor (CAR) biology: discovery and comparison of human CAR inverse agonists. Mol.Pharm. 8 2424 PMID:22044162