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D-Sedoheptulose 7-phosphate
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
D-Sedoheptulose 7-phosphate图片
CAS NO:2646-35-7
包装:5mg
市场价:14850元

产品介绍
D-Sedoheptulose7-phosphate是septacidin和hygromycinB等七肽的共同前体。D-Sedoheptulose7-phosphate通过类似的生物合成途径转化为可转化为NDP-heptoses。
Cas No.2646-35-7
Canonical SMILESOCC([C@H]([C@@H]([C@@H]([C@@H](COP(O)(O)=O)O)O)O)O)=O
分子式C7H15O10P
分子量290.16
储存条件Store at -20℃
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

D-Sedoheptulose 7-phosphate is a common precursor for the heptoses of septacidin (group III) and hygromycin B (group IV). D-Sedoheptulose 7-phosphate can be converted to NDP-heptoses through similar biosynthetic pathways in those compounds [1].

Sedoheptulose 7-phosphate can be converted to ADP-l-glycero-β-d-manno-heptose by SepB, SepL, and SepC, it involves in ADP-sugar in microbial natural product biosynthesis[1].SepB is an S-7-P isomerase, SepL involves in the biosynthesis of heptoses of the core region of E. coli LPS, and they catalyze a four-reaction relay converting S-7-P into ADP-d-glycero-β-d-manno-heptose [1].Septacidin and its analogs are potential anticancer and pain-relief agents[1].Hygromycin B is an anthelmintic agent practically used in swine and poultry farming[1].

[1]. Tang W, et al. d-Sedoheptulose-7-phosphate is a common precursor for the heptoses of septacidin and hygromycin B.Proc Natl Acad Sci U S A. 2018 Mar 13;115(11):2818-2823.