| CAS NO: | 1356354-25-0 |
| 包装: | 1mg |
| 市场价: | 1497元 |
| Cas No. | 1356354-25-0 |
| Canonical SMILES | [O-]C([C@@H]1N2[C@@](SC1(C)C)([H])[C@@H](C2=O)NC(C3=C(OC([2H])([2H])C([2H])([2H])[2H])C=CC4=C3C=CC=C4)=O)=O.[Na+] |
| 分子式 | C21H16D5N2O5S•Na |
| 分子量 | 441.5 |
| 溶解度 | DMSO: slightly soluble,Methanol: slightly soluble |
| 储存条件 | -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Nafcillin-d5is intended for use as an internal standard for the quantification of nafcillin by GC- or LC-MS. Nafcillin is a semisynthetic and penicillinase-resistant penicillin antibiotic.1It is active against 20 clinical isolates ofS. aureuswith minimum bactericidal concentration (MBC) values ranging from 0.078 to 0.312 µg/ml. Nafcillin (100-800 mg/kg) reduces the number of kidney colony forming units (CFUs) in a mouse model ofS. aureusinfection.2It also reduces the number of right atrial CFUs in a rabbit model ofS. aureus-induced endocarditis.3Formulations containing nafcillin have been used in the treatment of various bacterial infections. 1.Tuazon, C.U., Lin, M.Y., and Sheagren, J.N.In vitro activity of rifampin alone and in combination with nafcillin and vancomycin against pathogenic strains of Staphylococcus aureusAntimicrob. Agents Chemother.13(5)759-761(1978) 2.Yuchenco, J.A., Hopper, M.W., Vince, T.D., et al.Nafcillin and oxacillin: Comparative antistaphylococcal activity in miceJ. Antibiot. (Tokyo)29(4)460-465(1976) 3.Carrizosa, J., Kobasa, W.D., and Kaye, D.Effectiveness of nafcillin, methicillin, and cephalothin in experimental Staphylococcus aureus endocarditisAntimicrob. Agents Chemother.15(5)735-737(1979) |
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