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N-acetyl-L-Cysteine ethyl ester
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
N-acetyl-L-Cysteine ethyl ester图片
CAS NO:59587-09-6
包装与价格：
包装价格(元)
5mg电议
10mg电议
50mg电议
100mg电议

产品介绍

N-乙酰基-L-半胱氨酸乙酯是 N-乙酰基-L-半胱氨酸 (NAC) 的酯化形式。

Cas No.59587-09-6
别名N-乙酰-L-半胱氨酸乙酯,N-Acetylcysteine ethyl ester; NACET
Canonical SMILESSC[C@H](NC(C)=O)C(OCC)=O
分子式C7H13NO3S
分子量191.2
溶解度DMF: 30 mg/ml,DMSO: 30 mg/ml,PBS (pH 7.2): 10 mg/ml
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

N-acetyl-L-Cysteine ethyl ester is an esterified form of N-acetyl-L-cysteine . It has enhanced cell permeability in isolated perfused rat liver compared to NAC.1N-acetyl-L-Cysteine ethyl ester (1 mM) preventstert-butyl hydroperoxide-induced formation of methemoglobin in isolated human red blood cells. It increases glutathione levels in rat liver, kidney, heart, testis, and brain when administered at a dose of 50 mg/kg twice per day for two weeks. N-acetyl-L-Cysteine ethyl ester reduces increases in plasma aspartate aminotransferase (AST), alanine aminotransferase (ALT), and lactate dehydrogenase (LDH) levels induced by paracetamol in rats.

1.Giustarini, D., Milzani, A., Dalle-Donne, I., et al.N-Acetylcysteine ethyl ester (NACET): A novel lipophilic cell-permeable cysteine derivative with an unusual pharmacokinetic feature and remarkable antioxidant potentialBiochem. Pharmacol.84(11)1522-1533(2012)