| CAS NO: | 1638970-46-3 |
| 包装 | 价格(元) |
| 5mg | 电议 |
| 10mg | 电议 |
| Cas No. | 1638970-46-3 |
| 分子式 | C67H101N11O16 |
| 分子量 | 1316.58 |
| 溶解度 | DMSO : 180 mg/mL (136.72 mM; Need ultrasonic) |
| 储存条件 | 4°C, protect from light, stored under nitrogen |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Mc-Alanyl-Alanyl-Asparagine-PAB-MMAE (compound S6) is a potent anticancer agent, which can be specific activated by tumor microenvironment. Mc-Alanyl-Alanyl-Asparagine-PAB-MMAE can suppress tumor growth in mice (extracted from patent CN104147612A)[1]. Mc-Alanyl-Alanyl-Asparagine-PAB-MMAE (compound S6) (26.2 micro-rubbing/kg, IV, weekly for 4 weeks) suppresses tumor growth in mice bearing Panc-1 tumor[1]. [1]. Liu Chen, et al. Tumor microenvironment specific activated micromolecular targeted conjugate and application thereof. CN104147612A. |
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