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Anemoside B4
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
Anemoside B4图片
CAS NO:129741-57-7
包装:20mg
市场价:1796元

产品介绍
Anemoside B4 (Anemoside B4) 是白头翁 (Pulsatilla koreana Nakai)，在体外具有多种生物效应，包括增强降血糖、抗肿瘤、神经保护和抗血管生成活性。
Cas No.129741-57-7
别名白头翁皂甙B4,Chinensioside A; Pulchinenoside C; Pulchinenoside B4
化学名Chinensioside A; Pulchinenoside C; Pulchinenoside B4
Canonical SMILESC=C([C@]([C@@]12[H])([H])CC[C@]2(C(O[C@@]3([H])[C@@](O)([H])[C@](O)([H])[C@@](O)([H])[C@@](O3)([H])CO[C@@]4([H])[C@@](O)([H])[C@](O)([H])[C@@](O[C@@]5([H])[C@@](O)([H])[C@@](O)([H])[C@](O)([H])[C@](O5)([H])C)([H])[C@@](O4)([H])CO)=O)CC[C@@]6([C@]1([H])CC[
分子式C59H96O26
分子量1221.38
溶解度DMSO: 1 mg/ml,PBS (pH 7.2): 10 mg/ml
储存条件4°C, protect from light
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Pulchinenoside C (Anemoside B4) is Pulsatilla koreana Nakai that have many numerous biological effects in vitro, including enhancing hypoglycemic, anti-tumor, neuroprotective and anti-angiogenic activity.

Pulchinenoside C (Anemoside B4) can inhibit the secretion of IL-10; SSA, SSD and PNS up-regulated IL-2 expression[1]. Pulchinenoside C (Anemoside B4), with IC50 value more than 390 ug/mL. Anemoside B4 inhibits cell proliferation[2]. Pulchinenoside C (Anemoside B4) can significantly suppress the secretion of the inflammatory factor E-selectin by endothelial cells[3].

References:
[1]. Hu Y et al. Role of Chinese herbal medicinal ingredients in secretion of cytokines by PCV2-induced endothelial cells. J Immunotoxicol. 2016;13(2):141-7.
[2]. Liu M et al. Cytotoxicity of the compounds isolated from Pulsatilla chinensis saponins and apoptosis induced by 23-hydroxybetulinic acid. Pharm Biol. 2015 Jan;53(1):1-9.
[3]. Hu Y et al. Chinese herbal medicinal ingredients inhibit secretion of IL-6, IL-8, E-selectin and TXB2 in LPS-induced rat intestinal microvascular endothelial cells. Immunopharmacol Immunotoxicol. 2009;31(4):550-5.