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Propargyl-PEG9-OH
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Propargyl-PEG9-OH图片
CAS NO:2055022-35-8
包装:1g
市场价:3683元

产品介绍
Propargyl-PEG9-OH 是一种 PROTAC linker,属于 PEG 类。Propargyl-PEG9-OH 可用于合成一系列 PROTAC 分子。
Cas No.2055022-35-8
分子式C21H40O10
分子量452.54
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Propargyl-PEG9-OH is a PEG-basedPROTAC linkercan be used in the synthesis of PROTACs[1].

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

[1]. Satwik Kamtekar, et al. Modified biotin-binding proteins for immobilization. WO2019126734A1.