| CAS NO: | 922727-65-9 |
| 包装: | 1mg |
| 市场价: | 6033元 |
| Cas No. | 922727-65-9 |
| 别名 | BY1023-d6; SKF96022-d6 |
| Canonical SMILES | O=S(CC(N=CC=C1OC([2H])([2H])[2H])=C1OC([2H])([2H])[2H])C2=NC3=CC(OC(F)F)=CC=C3N2 |
| 分子式 | C16H9D6F2N3O4S |
| 分子量 | 389.4 |
| 溶解度 | Soluble in DMSO |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Pantoprazole-d6 is intended for use as an internal standard for the quantification of pantoprazole by GC- or LC-MS. Pantoprazole is a proton pump inhibitor that inhibits H+/K+-ATPase activity in porcine gastric membrane vesicles with an IC50 value of 6.8 μM.1 It reduces basal gastric acid secretion in pylorus-ligated rats (ED50 = 1.3 mg/kg) and inhibits mepirizole-induced increases in gastric acid secretion in an anesthetized rat model of gastric fistula (ED50 = 0.8 mg/kg).2 Pantoprazole inhibits formation of mepirizole-induced duodenal lesions in rats (ED50 = 0.5 mg/kg). Formulations containing pantoprazole have been used in the treatment of gastroesophageal reflux disease (GERD) and hypersecretory conditions, including Zollinger-Ellison Syndrome. References |
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