Vazegepant hydrochloride

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本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

1414976-20-7

包装与价格：

包装	价格(元)
1mg	电议
5mg	电议
10mg	电议
25mg	电议
50mg	电议

产品介绍

Vazegepant (BHV-3500) hydrochloride 是一种高度亲和性 CGRP 受体拮抗剂 (hCGRP Ki=0.023 nM)。Vazegepant hydrochloride 是第一种用于偏头痛的鼻用 gepant。Vazegepant hydrochloride 可能有助于有效管理 COVID-19 相关肺部炎症。

Cas No.	1414976-20-7
别名	Zavegepant hydrochloride; BHV-3500 hydrochloride
分子式	C₃₆H₄₇ClN₈O₃
分子量	675.26
溶解度	Water : 50 mg/mL (74.05 mM; Need ultrasonic)\|DMSO : 50 mg/mL (74.05 mM; Need ultrasonic)
储存条件	Store at -20°C
General tips	For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition	Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request
产品描述	Vazegepant (BHV-3500) hydrochloride is a highly affinity CGRP receptor antagonist (hCGRP Ki= 0.023 nM). Vazegepant hydrochloride is the first intranasal gepant for migraine. Vazegepant hydrochloride may be helpful in effective management of COVID-19 associated pulmonary inflammation[1][2][3]. [1]. Moreno-Ajona D, et al. Gepants, calcitonin-gene-related peptide receptor antagonists: what could be their role in migraine treatment•. Curr Opin Neurol. 2020;33(3):309-315. [2]. Mehta PP, et al. Novel and Evolving Therapies for COVID-19 Related Pulmonary Complications. Am J Med Sci. 2021;361(5):557-566. [3]. Moreno-Ajona D, PÉrez-RodrÍguez A, Goadsby PJ. Gepants, calcitonin-gene-related peptide receptor antagonists: what could be their role in migraine treatment•. Curr Opin Neurol. 2020;33(3):309-315.