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5(6)-Carboxy-2′,7′-dichlorofluorescein diacetate
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
5(6)-Carboxy-2′,7′-dichlorofluorescein diacetate图片
CAS NO:127770-45-0
包装与价格：
包装价格(元)
25mg电议
50mg电议
100mg电议

产品介绍
5(6)-Carboxy-&2#8242;,7′-dichlorofluorescein diacetate 是一种细胞透过性荧光指示剂。
Cas No.127770-45-0
别名5[6]-羧基-2',7'-二氯荧光素二乙酸酯
Canonical SMILESO=C(O1)C2=C(C=CC(C(O)=O)=C2)C31C4=CC(Cl)=C(OC(C)=O)C=C4OC5=C3C=C(Cl)C(OC(C)=O)=C5.O=C(O6)C7=C(C=C(C(O)=O)C=C7)C86C9=CC(Cl)=C(OC(C)=O)C=C9OC%10=C8C=C(Cl)C(OC(C)=O)=C%10
分子式C25H14Cl2O9
分子量529.3
溶解度DMF: 30 mg/ml,DMSO: 30 mg/ml
储存条件-20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

5(6)-Carboxy-2’,7’-dichlorofluorescein diacetate is an oxidant-sensitive and cell-permeable fluorescent probe.1Base hydrolysis of the ester bonds by intracellular esterases releases the acetate groups and the resulting compound, 5(6)-carboxy-2’,7’,-dichlorofluorescein, is oxidized by reactive oxygen species (ROS) and nitric oxide (NO) and displays excitation/emission maxima of 504 and 530 nm, respectively, which can be quantified as a measure of oxidant production.

1.Hempel, S.L., Buettner, G.R., O’Malley, Y.Q., et al.Dihydrofluorescein diacetate is superior for detecting intracellular oxidants: Comparison with 2’,7’-dichlorodihydrofluorescein diacetate, 5(and 6)-carboxy-2’,7’-dichlorodihydrofluorescein diacetate, and dihydrorhodamine 123Free Radic. Biol. Med.27(1-2)146-159(1999)