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GSK2881078
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
GSK2881078图片
CAS NO:1539314-06-1
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议

产品介绍
GSK 2881078 是一种选择性雄激素受体调节剂,可能用于治疗恶病质。
Cas No.1539314-06-1
化学名1-[(1R)-1-methyl-2-(methylsulfonyl)ethyl]-4-(trifluoromethyl)-1H-indole-5-carbonitrile
Canonical SMILESCS(C[C@@H](C)N1C2=CC=C(C#N)C(C(F)(F)F)=C2C=C1)(=O)=O
分子式C14H13F3N2O2S
分子量330.3
溶解度≤20mg/ml in ethanol;25mg/ml in DMSO;25mg/ml in dimethyl formamide
储存条件Store at -20℃
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

GSK2881078 is a potent and selective androgen receptor modulator (SARM) [1].

Steroidal nuclear receptor (NR) ligands play important roles in the health of both men and women. Dihydrotestosterone (DHT) and testosterone (T) are endogenous steroidal ligands for the androgen receptor (AR) that play a role in every tissue type found in the mammalian body. During the development of the fetus, androgens play an important role in sexual differentiation and development of male sexual organs. SARMs are small molecule pharmacotherapeutics that have the potential to afford the important benefits of androgen therapy without the undesired side-effects [1].

GSK2881078 is a potent and selective androgen receptor modulator (SARM) that is being evaluated for effects on muscle growth and strength in subjects with muscle wasting to improve their physical function. GSK2881078 is currently in phase I clinical trials [1].

Reference:
[1].  https://newdrugapprovals.org/2016/06/14/gsk-2881078/