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Tyr-Gly-Gly-Phe-Met-OH(Met-Enkephalin)
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
Tyr-Gly-Gly-Phe-Met-OH(Met-Enkephalin)图片
CAS NO:58569-55-4
包装与价格：
包装价格(元)
10mM (in 1mL Water)电议
25mg电议
50mg电议
100mg电议

产品介绍
Tyr-Gly-Gly-Phe-Met-OH (Met-Enkephalin) 通过与阿片受体结合来调节人体免疫功能并抑制肿瘤生长。
Cas No.58569-55-4
别名蛋氨酸脑啡肽; Met-Enkephalin; Methionine enkephalin
Canonical SMILESTyr-Gly-Gly-Phe-Met
分子式C27H35N5O7S
分子量573.66
溶解度DMSO : ≥ 40 mg/mL (69.73 mM);Water : 6.67 mg/mL (11.63 mM)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Tyr-Gly-Gly-Phe-Met-OH regulates human immune function and inhibits tumor growth via binding to the opioid receptor.

Methionine enkephalin (MENK), an endogenous neuropeptide has a crucial role in both neuroendocrine and immune systems. MENK is believed to have an immunoregulatory activity to have cancer biotherapy activity by binding to the opioid receptors on immune and cancer cells. MENK may also change the tumor microenvironment by binding to opioid receptor on or in cancer cells. All of these mechanisms of action have biologic significance and potential for use in cancer immunotherapy. Furthermore, they reveal a relationship between the endocrine and immune systems[1].

[1]. Zhao D, et al. Methionine enkephalin, its role in immunoregulation and cancer therapy. Int Immunopharmacol. 2016 Feb 23. pii: S1567-5769(16)30050-9.