CAS NO: | 199864-86-3 |
包装 | 价格(元) |
10mg | 电议 |
50mg | 电议 |
Cas No. | 199864-86-3 |
别名 | 4-(4-氟-1-萘基)-6-(1-甲基乙基)-2-嘧啶胺盐酸盐 |
Canonical SMILES | FC1=C(C=CC=C2)C2=C(C3=CC(C(C)C)=NC(N)=N3)C=C1.Cl |
分子式 | C17H16FN3.HCl |
分子量 | 317.79 |
溶解度 | Soluble in DMSO |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | High affinity 5-HT2B receptor antagonist (pKi = 9.5). Displays 1000-fold selectivity for 5-HT2B with good bioavailability. Bonhaus et al (1999) RS-127445: a selective, high affinity, orally bioavailable 5-HT2B receptor antagonist. Br.J.Pharmacol. 127 1075 PMID:10455251 |Callebert et al (2006) Evidence for a control of plasma serotonin levels by 5-Hydroxytryptamine2B receptors in mice. J.Pharmacol.Exp.Ther. 317 724 PMID:16461587 |