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Erucin
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Erucin图片
CAS NO:4430-36-8
包装与价格:
包装价格(元)
10mg电议
25mg电议
50mg电议

产品介绍
芥菜素 (ERU) 是一种异硫氰酸酯,在芝麻菜中含量特别丰富。
Cas No.4430-36-8
别名芥酸精; 甘油三芥酸酯
化学名1-isothiocyanato-4-(methylthio)-butane
Canonical SMILESCSCCCCN=C=S
分子式C6H11NS2
分子量161.3
溶解度16mg/mL in ehanol, 14mg/mL in DMSO, 12mg/mL in DMF
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Erucin is an isothiocyanate derived from glucoerucin, a glucosinolate predominant in arugula (Eruca sativa Mill.) and other cruciferous vegetables. At 2.5-5 μM erucin can induce significant neuroprotective and antioxidant effects, increasing both total glutathione levels and total antioxidant capacity at the cytosolic level in dopaminergic-like neuroblastoma SH-SY5Y cells.[1] Growth inhibition, cell cycle regulation, apoptosis, and induction of detoxification enzymes have all been reported from use of erucin in prostate, lung, liver, and colon cancer cells.[2][3]

Reference:
[1]. Tarozzi, A., Morroni, F., Bolondi, C., et al. Neuroprotective effects of erucin against 6-hydroxydopamine-induced oxidative damage in a dopaminergic-like neuroblastoma cell line. International Journal of Molecular Sciences 13, 10899-10910 (2012).
[2]. Melchini, A., and Traka, M.H. Biological profile of erucin: A new promising anticancer agent from cruciferous vegetables. Toxins 2, 593-612 (2010).
[3]. Zhang, Y., Talalay, P., Cho, C.G., et al. A major inducer of anticarcinogenic protective enzymes from broccoli: Isolation and elucidation of structure. Proceedings of the National Academy of Sciences of the United States of America 89, 2399-2403 (1992).