包装 | 价格(元) |
500μg | 电议 |
2.5mg | 电议 |
Canonical SMILES | C[C@H]([C@H](OC)/C(C)=C/C=C/CNC([C@@H](CC)[C@@]1(O)O[C@](/C=C\C=C/C)([H])C(C)(O)[C@@H](O)C1)=O)[C@]2([H])O[C@](/C=C/C=C/C=C/C(O)=O)([H])[C@@H](O)C2 |
分子式 | C36H53NO10 |
分子量 | 659.8 |
溶解度 | DMF: soluble,DMSO: soluble,Ethanol: soluble,Methanol: soluble |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | L-681,217 is an antibiotic originally isolated from S. cattleya. It is active against Gram positive and Gram negative bacteria when used at a concentration of 255 µg/ml. L-681,217 inhibits bacterial protein synthesis at the elongation stage, completely inhibiting poly(U)-dependent poly(Phe) synthesis (EC50 = 0.4 µM) and increasing elongation factor Tu (EF-Tu)-associated GTPase activity in E. coli (EC50 = 6 µM). It does not inhibit poly(U)-dependent poly(Phe) synthesis in S. aureus (EC50 = >1,000 µM). |