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Mitomycin A
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Mitomycin A图片
CAS NO:4055-39-4
包装与价格:
包装价格(元)
500μg电议
1mg电议
5mg电议

产品介绍
Cas No.4055-39-4
别名丝裂霉素A
Canonical SMILESCC(C(C1=C2[C@@H](COC(N)=O)[C@]3(OC)N1C[C@H]4[C@@H]3N4)=O)=C(OC)C2=O
分子式C16H19N3O6
分子量349.3
溶解度Chloroform: Slightly soluble,Methanol: Slightly soluble
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Mitomycin A is a bacterial metabolite originally isolated from S. caespitosus. It reduces migration inhibition factor (MIF) production by isolated human lymphocytes when used at a concentration of 0.25 µg/ml and decreases spontaneous migration of WEHI-3 murine monocytes when used at concentrations of 0.5 and 5 µg/ml. Mitomycin A forms intra- and interstrand adducts with DNA in the presence of thiols, such as dithiothreitol (DTT). It reduces tumor growth in P388 leukemia and B16 melanoma mouse models with a minimum effective dose (MED) of 0.05 mg/kg for both but is toxic to mice with an LD50 value of 2 mg/kg.