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Telomerase-IN-2
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Telomerase-IN-2图片
CAS NO:1610878-54-0
包装与价格:
包装价格(元)
10mM (in 1mL DMSO)电议
1mg电议
5mg电议
10mg电议
25mg电议
50mg电议
100mg电议
200mg电议
500mg电议

产品介绍
Telomerase-IN-2 是一种端粒酶 (telomerase) 抑制剂,通过降低角化不良蛋白的表达来抑制其活性,IC50 值为 0.89 µM。Telomerase-IN-2 具有抗癌作用。
Cas No.1610878-54-0
Canonical SMILESO=C1C(OCCCCN2CCN(C(C3=CC=NC=C3)=O)CC2)=C(C4=CC(OC)=C(OC)C(OC)=C4)OC5=CC(OC)=CC(OC)=C15
分子式C34H39N3O9
分子量633.69
溶解度DMSO: 250 mg/mL (394.51 mM)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Telomerase-IN-2 is a telomerase inhibitor, and inhibits telomerase activity by decreasing expression of dyskerin, with an IC50 of 0.89 µM. Anti-cancer activity[1].

[1]. Quan Wang J, et al. Discovery of new chromen-4-one derivatives as telomerase inhibitors through regulating expression of dyskerin. J Enzyme Inhib Med Chem. 2018 Dec;33(1):1199-1211.