RK-20448 is an ATP-competitive inhibitor of Lck, Src, KDR/VEGF2R, and Tie-2 (IC50s = 0.24, 1.19, 10.74, and 5.85 μM, respectively).
| Cas No. | 479501-40-1 |
| Canonical SMILES | NC1=C(C(C2=CC=C(OC3=CC=CC=C3)C=C2)=CN4[C@H]5CC[C@@H](N6CCN(C)CC6)CC5)C4=NC=N1 |
| 分子式 | C29H34N6O |
| 分子量 | 482.6 |
| 溶解度 | DMSO: 10 mM |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | RK-20448 is an ATP-competitive inhibitor of Lck, Src, KDR/VEGF2R, and Tie-2 (IC50s = 0.24, 1.19, 10.74, and 5.85 µM, respectively). It also inhibits BLK, Csk, Fyn, and Lyn (IC50s = 0.37, 4.27, 2.03, and 0.43 µM, respectively). RK-20448 is the cis isomer of A-419259 . |
m.cnreagent.com