SU 5214 是从专利 US5834504A、SU 5214 中提取的一种有效的 VEGFR2 抑制剂，IC50 分别为 14.8 μM (FLK-1) 和 36.7 μM (EGFR)。
| Cas No. | 186611-04-1 |
| 别名 | SU4949 |
| Canonical SMILES | O=C1/C(C2=CC=CC=C2N1)=C\C3=C(OC)C=CC=C3 |
| 分子式 | C16H13NO2 |
| 分子量 | 251.3 |
| 溶解度 | DMF: 33 mg/ml,DMSO: 33 mg/ml,DMSO:PBS(pH 7.2) (1:3): 0.25 mg/ml |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | SU 5214 is a 3-heteroaryl-2-indoline that was designed in a drug discovery program for development of tyrosine kinase inhibitors. |
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