| Cas No. | 174709-30-9 |
| Canonical SMILES | BrC1=CC=CC(NC2=C(C=C(N=CN3C)C3=C4)C4=NC=N2)=C1 |
| 分子式 | C16H12BrN5 |
| 分子量 | 354.2 |
| 溶解度 | DMF: 20 mg/ml,DMSO: 30 mg/ml,DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | BPIQ-I is a quinazoline that inhibits the tyrosine kinase activity of the epidermal growth factor receptor (IC50 = 0.025 nM). It can inhibit the growth of SKOV3 and MDA-468 tumor cell lines with EC50 values of 6.5 and 30 µM, respectively. |
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