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GTP 14564
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
GTP 14564图片
CAS NO:34823-86-4
包装与价格:
包装价格(元)
500μg电议
1mg电议
5mg电议

产品介绍
GTP 14564 is an inhibitor of class III receptor tyrosine kinases (IC50s = 0.3 μM for c-Fms, c-Kit, ITD-FLT3 and 1 μM for PDGFRβ).
Cas No.34823-86-4
Canonical SMILESC12=CC=CC=C1OC3=C2NN=C3C4=CC=CC=C4
分子式C15H10N2O
分子量234.3
溶解度DMF: 30 mg/ml,DMSO: 30 mg/ml,DMSO:PBS(pH 7.2) (1:2): 0.3 mg/ml,Ethanol: 1 mg/ml
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

GTP 14564 is an inhibitor of class III receptor tyrosine kinases (IC50s = 0.3 µM for c-Fms, c-Kit, ITD-FLT3 and 1 µM for PDGFRβ). It is without effect against a panel of non-receptor tyrosine and serine/threonine kinases. GTP 14564 blocks the proliferation of leukemia cells stimulated with FLT3 ligand by preventing the activation of STAT5.