| CAS NO: | 207737-97-1 |
| 包装 | 价格(元) |
| 1 g | 电议 |
| 5 g | 电议 |
| 25 g | 电议 |
| Cas No. | 207737-97-1 |
| 别名 | 牛磺脱氧胆酸钠水合物 |
| Canonical SMILES | O[C@@H]1CC[C@@]2(C)[C@@](CC[C@]3([H])[C@]2([H])C[C@H](O)[C@@]4(C)[C@@]3([H])CC[C@]4([H])[C@H](C)CCC(NCCS(=O)([O-])=O)=O)([H])C1.[Na+].O |
| 分子式 | C26H44NO6S·Na [XH2O] |
| 分子量 | 521.7 |
| 溶解度 | DMF: 25 mg/ml,DMSO: 20 mg/ml,Ethanol: 2 mg/ml,PBS (pH 7.2): 3 mg/ml |
| 储存条件 | -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Taurodeoxycholic acid is a taurine-conjugated form of the secondary bile acid deoxycholic acid .1Taurodeoxycholic acid stimulates chloride ion secretion through calcium-activated chloride ion channels and cystic fibrosis transmembrane conductance regulator (CFTR) in Calu-3 airway epithelial cell monolayers when applied basolaterally.2Serum levels of taurodeoxycholic acid increase approximately 5-fold within two hours during an oral lipid tolerance test in humans.1 1.Schmid, A., Neumann, H., Karrasch, T., et al.Bile acid metabolome after an oral lipid tolerance test by liquid chromatography-tandem mass spectrometry (LC-MS/MS)PLoS One11(2)e0148869(2016) 2.Hendrick, S.M., Mroz, M.S., Greene, C.M., et al.Bile acids stimulate chloride secretion through CFTR and calcium-activated Cl- channels in Calu-3 airway epithelial cellsAm. J. Physiol. Lung. Cell. Mol. Physiol.307(5)L407-L418(2014) |
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