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BRD4884
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
BRD4884图片
CAS NO:1404559-91-6
包装与价格:
包装价格(元)
500μg电议
1mg电议
5mg电议
10mg电议

产品介绍
BRD4884 是一种有效的 HDAC 抑制剂,对 HDAC1、2 和 3 的 IC50 值分别为 29 nM、62 nM 和 1.09 μM。
Cas No.1404559-91-6
Canonical SMILESFC1=CC=C(C2=CC=C(N)C(NC(C3CCOCC3)=O)=C2)C=C1
分子式C18H19FN2O2
分子量314.4
溶解度DMF: 30 mg/mL,DMSO: 30 mg/mL,DMSO:PBS (pH 7.2) (1:1): 0.5 mg/mL,Ethanol: 2 mg/mL
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

BRD4884 is an HDAC inhibitor with IC50 values of 29 nM, 62 nM, and 1.09 µM for HDAC1, 2, and 3, respectively. It possesses preferential binding kinetics with seven-fold longer half-life on HDAC2 compared to HDAC1 (143 min versus 20 min). BRD4884 crosses the blood brain barrier and has been evaluated in CK-p25 mice, a mouse model of neurodegeneration.