Amodiaquine (Amodiaquin) 是一种 4-氨基喹啉类抗疟药,是一种有效且具有口服活性的组胺 N-甲基转移酶抑制剂。
Cas No. | 86-42-0 |
别名 | 阿莫地喹,Amodiaquin |
Canonical SMILES | OC(C=C1)=C(CN(CC)CC)C=C1NC2=CC=NC3=C2C=CC(Cl)=C3 |
分子式 | C20H22ClN3O |
分子量 | 355.9 |
溶解度 | DMF: 2.5 mg/ml,DMSO: 5 mg/ml,Ethanol: 2 mg/ml |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Amodiaquine is an aminoquinoline antimalarial compound. It is metabolized primarily by cytochrome P450 2C8 to N-desethylaminodiaquine, which is highly active against P. falciparum and can synergize with amodiaquine. Amodiaquine is commonly used in combination therapy. |