| CAS NO: | 60-01-5 |
| 包装: | 5 mL |
| 市场价: | 540元 |
| Cas No. | 60-01-5 |
| 别名 | 甘油三丁酸酯,Glyceryl tributyrate |
| Canonical SMILES | CCCC(OCC(OC(CCC)=O)COC(CCC)=O)=O |
| 分子式 | C15H26O6 |
| 分子量 | 302.36 |
| 溶解度 | DMSO: 100 mg/mL (330.73 mM) |
| 储存条件 | Store at -20℃ |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Tributyrin (Glyceryl tributyrate), a neutral short-chain fatty acid triglyceride, is a stable and rapidly absorbed prodrug of Butyric Acid. Tributyrin diffuses through biological membranes and is metabolized by intracellular lipases, releasing effective butyrate directly into the cell in vivo. Tributyrin has potent antiproliferative, proapoptotic and differentiation-inducing effects[1]. [1]. T Gaschott, et al. Tributyrin, a stable and rapidly absorbed prodrug of butyric acid, enhances antiproliferative effects of dihydroxycholecalciferol in human colon cancer cells. J Nutr. 2001 Jun;131(6):1839-43. [2]. Claudia P SchrÖder, et al. Tributyrin-induced differentiation promotes apoptosis of LS 174T colon cancer cells in vitro. Int J Oncol. 2002 Jan;20(1):195-200. |
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