| CAS NO: | 605-62-9 |
| 包装 | 价格(元) |
| 5 g | 电议 |
| 10 g | 电议 |
| Cas No. | 605-62-9 |
| 别名 | 4-硝基-1-萘酚 |
| 分子式 | C10H7NO3 |
| 分子量 | 189.17 |
| 储存条件 | 4°C, stored under nitrogen |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | KAT8-IN-1 is a lysine (K) acetyltransferase 8 (KAT8) inhibitor, with IC50s of 141 μM (KAT8), 221 μM (KAT2B), 106 μM (KAT3B), respectively. KAT8 inhibits histone acetyltransferases (HATs), and could result in disease states, such as cancer or inflammatory diseases[1]. KAT8-IN-1 (compound 19) losses anti-oxidant activity (EC50>1 mM)[1]. [1]. Wapenaar H, et al. The relevance of Ki calculation for bi-substrate enzymes illustrated by kinetic evaluation of a novel lysine (K) acetyltransferase 8 inhibitor. Eur J Med Chem. 2017 Aug 18;136:480-486. |
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