您好,欢迎来到试剂仪器网! [登录] [免费注册]
试剂仪器网
位置:首页 > 产品库 > GSK854
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
GSK854
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
GSK854图片
CAS NO:1316059-00-3
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议
50mg电议

产品介绍
GSK854 是一种有效的肌钙蛋白 I 相互作用激酶 (TNNI3K) 抑制剂。GSK854 是一种合适的先导药物,可用于识别新的心脏药物,并已在旨在确定 TNNI3K 在心力衰竭中的作用的研究中用作体内工具。
Cas No.1316059-00-3
分子式C18H19ClN6O4S2
分子量482.96
溶解度DMSO : 250 mg/mL (517.64 mM; Need ultrasonic)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

GSK854 is a potent Inhibitor of Troponin I-Interacting Kinase (TNNI3K). GSK854 is a suitable lead for identifying new cardiac medicines and have been employed as in vivo tools in investigational studies aimed at defining the role of TNNI3K within heart failure[1].

[1]. Philp J, et al. 4,6-Diaminopyrimidines as Highly Preferred Troponin I-Interacting Kinase (TNNI3K) Inhibitors. J Med Chem. 2018;61(7):3076-3088.