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GSK329
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
GSK329图片
CAS NO:1268490-12-5
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议
50mg电议
100mg电议

产品介绍
GSK329 是一种有效和选择性的心脏特异性激酶 TNNI3K 的二芳基脲抑制剂。 GSK329 在缺血/再灌注心脏损伤模型中表现出积极的心脏保护结果。
Cas No.1268490-12-5
分子式C19H14Cl2F3N5O2
分子量472.25
溶解度DMSO : 250 mg/mL (529.38 mM; Need ultrasonic)
储存条件4°C, protect from light
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

GSK329 is a potent and selective diarylurea inhibitor of the cardiac-specific kinase TNNI3K. GSK329 exhibits positive cardioprotective outcomes in the model of ischemia/reperfusion cardiac injury[1].

[1]. Patterson JR, et, al. Identification of Diarylurea Inhibitors of the Cardiac-Specific Kinase TNNI3K by Designing Selectivity Against VEGFR2, p38α, and B-Raf. J Med Chem. 2021 Nov 11;64(21):15651-15670.