| CAS NO: | 191744-13-5 |
| 包装 | 价格(元) |
| 10mg | 电议 |
| 50mg | 电议 |
| Cas No. | 191744-13-5 |
| 别名 | 2,3,6A,7,8,9-六氢-11H-1,4-二恶烷并[2,3-G]吡咯并[2,1-B][1,3]苯并恶嗪-11-酮 |
| Canonical SMILES | O=C2N4C(CCC4)OC1=CC3=C(OCCO3)C=C12 |
| 分子式 | C13H13NO4 |
| 分子量 | 247.25 |
| 溶解度 | Soluble in DMSO |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | AMPAkine; positive allosteric modulator of AMPA. Prototypical benzamide which occupies subsite A only. Modulates channel deactivation and desensitization. Harms et al (2013) Functional analysis of a novel positive allosteric modulator of AMPA receptors derived from a structure-based drug design strategy. Neuropharmacology 64 45 PMID:22735771 |Timm et al (2011) Structural and functional analysis of two new positive allosteric modulators of GluA2 desensitization and deactivation. Mol.Pharmacol. 80 267 PMID:21543522 |Hennegriff et al (1997) Stable expression of recombinant AMPA receptor subunits: binding affinities and effects of allosteric modulators. J.Neurochem. 68 2424 PMID:9166736 |
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