| CAS NO: | 688309-70-8 |
| 包装 | 价格(元) |
| 10mg | 电议 |
| 50mg | 电议 |
| Cas No. | 688309-70-8 |
| Canonical SMILES | CC(C)C1=CC(Br)=C(NC(NC2=CN=CC=C2)=O)C(Br)=C1 |
| 分子式 | C15H15Br2N3O |
| 分子量 | 413.11 |
| 溶解度 | DMSO: 30 mg/ml |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Selective P2X4 allosteric antagonist (IC50 = 0.54 μM). Exhibits >10-fold selectivity for human P2X4 receptors over P2X1, P2X2, P2X3, P2X5 and P2X7 receptors. Binds noncompetitively at extracellular allosteric site. Effective at human and zebrafish, but not mouse and rat P2X4 receptors. Ase et al (2015) Identification and characterization of a selective allosteric antagonist of human P2X4 receptor channels Mol.Pharmacol. 87 606 PMID:25597706 |
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