您好,欢迎来到试剂仪器网! [登录] [免费注册]
试剂仪器网
位置:首页 > 产品库 > AMP PNP
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
AMP PNP
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
AMP PNP图片
CAS NO:72957-42-7
包装:10mg
市场价:2381元

产品介绍
AMP PNP (Adenylyl-imidodiphosphate tetralithium) 是一种不可水解的 ATP 类似物,可抑制 KATP 通道。
Cas No.72957-42-7
别名腺苷-5'-(Β,Γ-亚氨基)三磷酸四锂,Adenylyl imidodiphosphate
Canonical SMILESNC1=C2C(N([C@@H]3O[C@H](COP(OP(NP([O-])([O-])=O)([O-])=O)([O-])=O)[C@@H](O)[C@H]3O)C=N2)=NC=N1.[Li+].[Li+].[Li+].[Li+]
分子式C10H13Li4N6O12P3
分子量529.93
溶解度26.5mg/ml in water
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Non-hydrolyzable AMP analog. Kir6 (KATP) channel blocker. Inhibits fast axonal transport and stabilizes the interaction of membranous organelles with microtubules.

Brady (1985) A novel brain ATPase with properties expected for the fast axonal transport motor. Nature 317 73 PMID:2412134 |Yount et al (1971) Adenylyl imidodiphosphate, an adenosine triphosphate analog containing a P-N-P linkage. Biochemistry 10 2484 PMID:4326768 |Hehl and Neumcke (1994) KATP channels of mouse skeletal muscle: mechanism of channel blockage by AMP-PNP. Eur.Biophys.J. 23 231 PMID:7805625