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(2R/S)-6-PNG
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
(2R/S)-6-PNG图片
CAS NO:68682-01-9
包装:5mg
市场价:2720元

产品介绍
(2R/S)-6-PNG (6-Prenylnaringenin) 是一种有效且可逆的 Cav3.2 T 型 Ca2+ 通道 (T-channels) 阻滞剂。
Cas No.68682-01-9
别名6-Prenylnaringenin
Canonical SMILESC/C(C)=C\CC1=C(C=C2OC(C3=CC=C(C=C3)O)CC(C2=C1O)=O)O
分子式C20H20O5
分子量340.37
溶解度Soluble in DMSO
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Cav3.2 (T-type) Ca2+ channel blocker (IC50 = 991 nM). Suppresses neuropathic allodynia in mouse pain models.

Sekiguchi et al (2018) Blockade of T-type calcium channels by 6-prenylnaringenin, a hop component, alleviates neuropathic and visceral pain in mice. Neuropharmacology 138 232 PMID:29913186