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H3B-120
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
H3B-120图片
CAS NO:2194903-42-7
包装与价格:
包装价格(元)
5mg电议
10mg电议
50mg电议
100mg电议

产品介绍
H3B-120 是一种高选择性,竞争性和变构的氨基甲酰磷酸合成酶 1 (CPS1) 抑制剂,IC50 为 1.5 μM,Ki 为 1.4 μM。H3B-120 具有抗癌活性。
Cas No.2194903-42-7
Canonical SMILESO=C(N1CCC(C(NC2=NC(C)=CS2)=O)CC1)N(C)CC3=CC=CC=C3
分子式C19H24N4O2S
分子量372.48
溶解度DMSO: 62.5 mg/mL (167.79 mM)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

H3B-120 is a highly selective, competitive and allosteric carbamoyl phosphate synthetase 1 (CPS1) inhibitor with an IC50 of 1.5 μM and a Ki of 1.4 μM. H3B-120 has anti-cancer activity[1].

[1]. Yao S, et al. Small Molecule Inhibition of CPS1 Activity through an Allosteric Pocket. Cell Chem Biol. 2020 Mar 19;27(3):259-268.