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(2S)-6-Prenylnaringenin
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
(2S)-6-Prenylnaringenin图片
CAS NO:68236-13-5
包装与价格：
包装价格(元)
1mg电议
5mg电议
10mg电议

产品介绍
(2S)-6-Prenylnaringenin是前脑中最有效的化合物。(2S)-6-Prenylnaringenin在α+β结合位点上起GABAA正变构调节剂的作用。
Cas No.68236-13-5
别名(2S)-6-异戊烯基柚皮素
Canonical SMILESOC1=C2C(O[C@H](C3=CC=C(O)C=C3)CC2=O)=CC(O)=C1C/C=C(C)/C
分子式C20H20O5
分子量340.37
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

(2S)-6-Prenylnaringenin is the most efficient compound in forebrain. (2S)-6-Prenylnaringenin acts as a GABAA positive allosteric modulator at α+β- binding interface[1].

(2S)-6-Prenylnaringenin (6-Prenylnaringenin) displays a modulatory activity at low micromolar concentrations. (2S)-6-Prenylnaringenin potentiates GABA-induced displacement of [3H]EBOB binding in a concentration-dependent manner where the IC50 value for this potentiation in native GABAA receptors is 3.7 μM, respectively[1].

[1]. Ali Y Benkherouf, et al. Hops Compounds Modulatory Effects and 6-prenylnaringenin Dual Mode of Action on GABA AReceptors. Eur J Pharmacol. 2020 Apr 15;873:172962.