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Nadolol
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Nadolol图片
CAS NO:42200-33-9
包装与价格:
包装价格(元)
10mM (in 1mL DMSO)电议
100mg电议
250mg电议
500mg电议

产品介绍
Nadolol (SQ-11725) 是一种非选择性的具有口服活性的 β-肾上腺素受体 (β-adrenergic receptors) 阻滞剂,也是有机阴离子转运多肽 1A2 (OATP1A2) 的一种底物。Nadolol 可用于高血压,心绞痛和血管性头痛的研究。
Cas No.42200-33-9
别名纳多洛尔; SQ-11725
Canonical SMILESOC1CC2=C(C(OCC(O)CNC(C)(C)C)=CC=C2)CC1O
分子式C17H27NO4
分子量309.4
溶解度Methanol: 250 mg/mL (808.02 mM)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Nadolol (SQ-11725) is a non-selective and orally active β-adrenergic receptors blocker and is a substrate of organic anion transporting polypeptide 1A2 (OATP1A2). Nadolol has the the potential for high blood pressure, angina pectoris and vascular headaches research[1][2][3].

[1]. Johannes C von Alvensleben, et al. Nadolol for Treatment of Supraventricular Tachycardia in Infants and Young Children. Pediatr Cardiol. 2017 Mar;38(3):525-530. [2]. Osamu Abe, et al. Role of (-)-Epigallocatechin Gallate in the Pharmacokinetic Interaction Between Nadolol and Green Tea in Healthy Volunteers. Eur J Clin Pharmacol. 2018 Jun;74(6):775-783. [3]. O Vegas, et al. Effects of Antalarmin and Nadolol on the Relationship Between Social Stress and Pulmonary Metastasis Development in Male OF1 Mice. Behav Brain Res. 2009 Dec 14;205(1):200-6.