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Resiquimod-d5
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
Resiquimod-d5图片
CAS NO:2252319-44-9
包装与价格：
包装价格(元)
5mg电议
10mg电议

产品介绍
Resiquimod-d5 (R848-d5) 是 Resiquimod 的氘代物。Resiquimod 是一种 TLR7/TLR8 的激动剂， 可诱导细胞因子如 TNF-α，IL-6 和 IFN-α 的上调。
Cas No.2252319-44-9
别名R848-d5; S28463-d5
分子式C17H17D5N4O2
分子量319.41
溶解度DMSO : 50 mg/mL (156.54 mM; Need ultrasonic)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Resiquimod-d5 (R848-d5) is deuterium labeled Resiquimod. Resiquimod is a Toll-like receptor 7 and 8 (TLR7/TLR8) agonist that induces the upregulation of cytokines such as TNF-α, IL-6 and IFN-α[1][2].

[1]. Sachan S, et al. Adjuvant potential of resiquimod with inactivated Newcastle disease vaccine and its mechanism of action in chicken. Vaccine. 2015 Aug 26;33(36):4526-32.
[2]. Zhou ZX, et al. Immune effects of R848: evidences that suggest an essential role of TLR7/8-induced, Myd88- and NF-κB-dependent signaling in the antiviral immunity of Japanese flounder (Paralichthys olivaceus). Dev Comp Immunol. 2015 Mar;49(1):113-20.