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Enrofloxacin-d5
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Enrofloxacin-d5图片
CAS NO:1173021-92-5
包装与价格:
包装价格(元)
1mg电议
5mg电议
10mg电议

产品介绍
An internal standard for the quantification of enrofloxacin
Cas No.1173021-92-5
别名恩诺沙星-D5,BAY Vp 2674-d5; PD160788-d5
Canonical SMILESO=C1C2=CC(F)=C(N3CCN(CC3)C([2H])([2H])C([2H])([2H])[2H])C=C2N(C4CC4)C=C1C(O)=O
分子式C19H17D5FN3O3
分子量364.4
溶解度DMF: 10 mg/ml,DMF:PBS (pH 7.2) (1:1): 0.5 mg/ml,DMSO: 1 mg/ml
储存条件-20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Enrofloxacin-d5is intended for use as an internal standard for the quantification of enrofloxacin by GC- or LC-MS. Enrofloxacin is a fluoroquinolone antibiotic.1It is active against panels ofCampylobacter,E. coli, andSalmonellaisolates (mean MIC50s = 0.06, 0.5, and 0.03 µg/ml, respectively). It is also active against equine isolates ofL. intracellularis(MICs = 0.125-0.5 µg/ml).2Enrofloxacin inhibits bacterial DNA gyrase.3In vivo, enrofloxacin (10 mg/kg) increases survival in a mouse model of enteropathogenicE. coli-induced sepsis. Formulations containing enrofloxacin have been used in the treatment of veterinary bacterial infections.

1.Randall, L., Ridley, A., Lemma, F., et al.In vitro investigations into the use of antimicrobials in combination to maintain efficacy of fluoroquinolones in poultryRes. Vet. Sci.10847-53(2016) 2.Pereira, C.E.R., Resende, T.P., Vasquez, E., et al.In vitro antimicrobial activity against equine Lawsonia intracellularis strainsEquine Vet. J.51(5)665-668(2019) 3.Slate, A.R., Bandyopadhyay, S., Francis, K.P., et al.Efficacy of enrofloxacin in a mouse model of sepsisJ. Am. Assoc. Lab. Anim. Sci.53(4)381-386(2014)