| 包装 | 价格(元) |
| 100mg | 电议 |
| 250mg | 电议 |
| 500mg | 电议 |
| 1 g | 电议 |
| Canonical SMILES | OC(C1=C(SC2CN(C3=NCCS3)C2)[C@H](C)[C@@]([C@]4([C@H](O)C)[H])([H])N1C4=O)=O.OOC(C1=C(SC2CN(C3=NCCS3)C2)[C@H](C)[C@@]([C@]4([C@H](O)C)[H])([H])N1C4=O)=O.O |
| 分子式 | C16H21N3O4S2·XH2O |
| 分子量 | 383.5 |
| 溶解度 | DMSO: 1 mg/ml,PBS (pH 7.2): 1 mg/ml |
| 储存条件 | -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Tebipenem is a carbenapenem antibiotic.1,2It is active against a panel of clinical isolates from a variety of bacterial species (MIC50s = ≤0.0039-8 µg/ml), including methicillin-resistant strains ofS. aureusandS. epidermidisand penicillin-resistantS. pneumoniae.1Tebipenem inhibits β-lactamase in a concentration-dependent manner.2It decreases the number of colony forming units (CFUs) in the lungs in a mouse model of penicillin-resistantS. pneumoniaeinfection when administered at doses ranging from 0.32 to 3.2 mg/kg.1 1.Fujimoto, K., Takemoto, K., Hatano, K., et al.Novel carbapenem antibiotics for parenteral and oral applications: In vitro and in vivo activities of 2-aryl carbapenems and their pharmacokinetics in laboratory animalsAntimicrob. Agents Chemother.57(2)697-707(2013) 2.Hazra, S., Xu, H., and Blanchard, J.S.Tebipenem, a new carbapenem antibiotic, is a slow substrate that inhibits the β-lactamase from Mycobacterium tuberculosisBiochemistry53(22)3671-3678(2014) |
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