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Cytidine 5'-triphosphate(sodium salt hydrate)
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
Cytidine 5'-triphosphate(sodium salt hydrate)图片
CAS NO:652154-13-7
包装与价格：
包装价格(元)
100mg电议
250mg电议
500mg电议
1 g电议

产品介绍
A pyrimidine nucleoside triphosphate
Cas No.652154-13-7
别名胞嘧啶核苷5`-三磷酸二钠盐水合物
Canonical SMILESO=P(OP(OP(O)([O-])=O)(O)=O)([O-])OC[C@H]1O[C@@H](N2C(N=C(N)C=C2)=O)[C@H](O)[C@@H]1O.[Na+].[Na+].O
分子式C9H14N3O14P3.2Na [XH2O]
分子量527.1
溶解度PBS (pH 7.2): 10 mg/ml
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Cytidine 5'-triphosphate (CTP) is a pyrimidine nucleoside triphosphate that is involved in a variety of biochemical reactions. It is used in the synthesis of RNA by RNA polymerases. In the formation of phosphatidylcholine (PC), CTP reacts with phosphocholine,viaCTP:phosphocholine cytidylyltransferases, to produce CDP-choline and diphosphate.1,2This is the rate-limiting step in PC synthesis and, as a pivotal step in cell proliferation, can be important in cancer.3CTP also interacts with N-acylneuraminate, in a reaction mediated by N-acylneuraminate cytidylyltransferase, to generate an intermediate that is required for sialylation, namely CMP-N-acylneuraminic acid.4

1.Li, Z., and Vance, D.E.Phosphatidylcholine and choline homeostasisJournal of Lipid Research491187-1194(2008) 2.Lagace, T.A., and Ridgway, N.D.The role of phospholipids in the biological activity and structure of the endoplasmic reticulumBiochim.Biophys.Acta.18332499-2510(2013) 3.Arsenault, D.J., Yoo, B.H., Rosen, K.V., et al.ras-Induced up-regulation of CTP:phosphocholine cytidyltransferase a contributes to malignant transformation of intestinal epithelial cellsThe Journal of Biological Chemisty288(1)633-643(2013) 4.Vionnet, J., Concepcion, N., Warner, T., et al.Purification of CMP-N-acetylneuraminic acid synthetase from bovine anterior pituitary glandsGlycobiology9(5)481-487(1999)