SU 5205 是 VEGFR2 (FLK-1) 的抑制剂，IC50 为 9.6 μM。
| Cas No. | 3476-86-6 |
| Canonical SMILES | FC1=CC=C(/C=C2C(NC3=C\2C=CC=C3)=O)C=C1 |
| 分子式 | C15H10FNO |
| 分子量 | 239.2 |
| 溶解度 | DMF: 50 mg/ml,DMSO: 50 mg/ml,DMSO:PBS(pH 7.2) (1:3): 0.25 mg/ml,Ethanol: 5 mg/ml |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | SU 5205 is an inhibitor of VEGF receptor 2 (VEGFR2/FLK1; IC50 = 9.6 µM). It inhibits human umbilical vein endothelial cell (HUVEC) mitogenesis induced by VEGF or acidic FGF with IC50 values of 0.9 and 0.6 µM, respectively. |
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