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2-Phospho-L-ascorbic acid trisodium salt
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
2-Phospho-L-ascorbic acid trisodium salt图片
CAS NO:66170-10-3
包装与价格:
包装价格(元)
Free Sample (0.1-0.5mg)电议
1g电议
5g电议
10g电议

产品介绍
2-Phospho-L-ascorbic acid trisodium salt (2-Phospho-L-ascorbic acid trisodium) 是一种长效维生素 C 衍生物,可刺激胶原蛋白的形成和表达。
Cas No.66170-10-3
别名L-抗坏血酸-2-磷酸三钠盐; 2-Phospho-L-ascorbic acid trisodium
Canonical SMILESO[C@@H](CO)[C@@H](O1)C(O[Na])=C(OP(O[Na])(O[Na])=O)C1=O
分子式C6H6Na3O9P
分子量322.05
溶解度Water : 150 mg/mL (465.77 mM) DMSO : 6 mg/mL (18.63 mM)
储存条件Store at RT
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

2-Phospho-L-ascorbic acid trisodium salt acts as an antioxidant and a stimulator of hepatocyte growth factor (HGF) production. Human Endogenous Metabolite

2-Phospho-L-ascorbic acid (Asc 2-P) acts as an antioxidant and a stimulator of hepatocyte growth factor (HGF) production. 2-Phospho-L-ascorbic acid is a stable derivative of L-ascorbic acid (AA) and possesses similar biological properties as AA. AA and Asc-2P regulate a number of biological processes[1]. When 2-Phospho-L-ascorbic acid is added together with DHT, DHT-induced DKK-1 mRNA expression in DPCs is significantly attenuated. It is also found that DKK-1 promoter activity is increased by DHT treatmen. When 2-Phospho-L-ascorbic acid is added together with DHT, DHT-induced activation of luciferase activity is significantly repressed[2].

[1]. Bae SH, et al. L-ascorbic acid 2-phosphate and fibroblast growth factor-2 treatment maintains differentiation potential in bone marrow-derived mesenchymal stem cells through expression of hepatocyte growth factor. Growth Factors. 2015 Apr;33(2):71-8. [2]. Kwack MH, et al. L-ascorbic acid 2-phosphate represses the dihydrotestosterone-induced dickkopf-1 expression in human balding dermal papilla cells. Exp Dermatol. 2010 Dec;19(12):1110-2.