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c-Fms-IN-3
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
c-Fms-IN-3图片
CAS NO:885704-21-2
包装与价格:
包装价格(元)
10mM (in 1mL DMSO)电议
5mg电议
10mg电议
50mg电议
100mg电议

产品介绍
c-Fms-IN-3 是c-Fms (CSF1R) 激酶抑制剂,具有抗炎抗风湿活性。
Cas No.885704-21-2
别名4-氰基-N-[4-(4-甲基-1-哌嗪基)-2-(4-甲基-1-哌啶基)苯基]-1H-吡咯-2-甲酰胺
Canonical SMILESCN(CC1)CCN1C2=CC=C(NC(C3=CC(C#N)=CN3)=O)C(N4CCC(C)CC4)=C2
分子式C23H30N6O
分子量406.52
溶解度DMSO: 25 mg/mL (61.50 mM); Water:< 0.1 mg/mL (insoluble)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

c-Fms-IN-3 is a novel c-Fms kinase inhibitor with a potential as anti-inflammatory agent and antirheumatic agent. c-Fms.

[1]. Meegalla, Sanath K.; Wall, Mark J.; Chen, Jinsheng et al. Structure-based optimization of a potent class of arylamide FMS inhibitors. Bioorganic & Medicinal Chemistry Letters (2008), 18(12), 3632-3637. [2]. Illig, Carl R.; Chen, Jinsheng; Wall, Mark J. et al. Discovery of novel FMS kinase inhibitors as anti-inflammatory agents. Bioorganic & Medicinal Chemistry Letters (2008), 18(5), 1642-1648.