DCA 是癌细胞中的代谢调节剂';具有抗癌活性的线粒体。 DCA 抑制 PDHK,导致肿瘤微环境中的乳酸减少。 DCA 增加活性氧 (ROS) 生成并促进癌细胞凋亡。 DCA 也可作为 NKCC 抑制剂。
Cas No. | 2156-56-1 |
别名 | 二氯乙酸钠 |
化学名 | sodium 2,2-dichloroacetate |
Canonical SMILES | ClC(C([O-])=O)Cl.[Na+] |
分子式 | C2HCl2NaO2 |
分子量 | 150.92 |
溶解度 | ≥ 15.1mg/mL in DMSO with gentle warming |
储存条件 | Desiccate at RT |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |