| 包装: | 1mg |
| 市场价: | 3024元 |
| 别名 | Glycine hyocholate-d4 |
| Canonical SMILES | O[C@@H]1C([2H])([2H])C[C@@]2(C)[C@@]([C@@H](O)[C@@H](O)[C@]3([H])[C@]2([H])CC[C@@]4(C)[C@@]3([H])CC[C@]4([H])[C@H](C)CCC(NCC(O)=O)=O)([H])C1([2H])[2H] |
| 分子式 | C26H39D4NO6 |
| 分子量 | 469.7 |
| 溶解度 | DMF: 30 mg/ml,DMF:PBS (pH 7.2) (1:1): 0.5 mg/ml,DMSO: 20 mg/ml,Ethanol: 20 mg/ml |
| 储存条件 | -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Glycohyocholic Acid-d4(GHCA-d4) is intended for use as an internal standard for the quantification of GHCA by GC- or LC-MS. GHCA is a glycine-conjugated form of the primary bile acid hyocholic acid .1GHCA is upregulated 6.6-fold in the serum of patients with cirrhosis induced by hepatitis C virus (HCV) compared to healthy controls.2Plasma levels of GHCA increase in patients who are no longer diabetic following gastric bypass surgery.3 1.Guo, L., Milburn, M.V., Ryals, J.A., et al.Plasma metabolomic profiles enhance precision medicine for volunteers of normal healthProc. Nat. Acad. Sci. USA112(35)E4901-E4910(2015) 2.Fitian, A.I., Nelson, D.R., Liu, C., et al.Integrated metabolomic profiling of hepatocellular carcinoma in hepatitis C cirrhosis through GC/MS and UPLC/MS-MSLiver Int.34(9)1428-1444(2014) 3.Yu, H., Ni, Y., Bao, Y., et al.Chenodeoxycholic acid as a potential prognostic marker for Roux-en-Y gastric bypass in Chinese obese patientsJ. Clin. Endocrinol. Metab.100(11)4222-4230(2015) |
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